The Effect of a Natural Compound (Taxadrol®) on Testosterone Level in two Species
Courtesy of All American Pharmaceutical, Billings Montana
The study was performed to assess the short-term benefits and possible side effects of Taxadrol® in rats and in human beings. This study was also intended to provide information on the potential health benefits and side effects of Taxadrol® for athletes, or any males, suffering from low testosterone levels.
Taxadrol® is a mixture of botanical extracts derived from several all natural plant sources. These extracts are believed to be acting by either suppressing estrogen production/transformation, or encouraging the production of male hormone precursors. The action of increased testosterone production has been observed across species – in male Wistar rats, and in men.
A total of 160 male Wistar rats were randomly distributed in sixteen treatment groups. Taxadrol treatment ranged from 4 mg/kg to 16 mg/kg, twice daily, via the oral rout using a gastric tube. The treatment period ranged from 10 days to 31 days depending upon group. Animals were sacrificed and blood samples were assayed for testosterone levels at the close of the treatment period.
A total of three human male participants self-administered Taxadrol at a dose of 30 mg – once to three times daily, sublingually. Testosterone levels were measured before the initiation of the study and at its close.
Following 17 days treatment there was a prominent, statistically significant increase in the levels total testosterone in the animals treated with the lower doses (4 and 8 mg/kg, twice daily). In animals treated with 8 mg/kg/twice daily, testosterone levels – both free and total, remained higher vs. the control group even after abstaining for 7 days.
TAXADROL® exerts modulating effects on testosterone levels in the rat and in man. Short term use, at the dosages tested, is not associated with toxicity.